Foto: Andreas Reeg, mail@andreasreeg.com, +49 171 544 92 47, www.andreasreeg.com
Foto: Andreas Reeg, mail@andreasreeg.com, +49 171 544 92 47, www.andreasreeg.com

Post-Doctoral Position in Tumor Biology focusing on Tumor Microenvironment of Colorectal Cancer (m/f/d)


The Georg-Speyer-Haus – Institute for Tumor Biology and Experimental Therapy in Frankfurt am Main is an academic non-profit research institute supported by the Federal Ministry of Health and the Ministry for Sciences and Arts of the State of Hessen. The institute is dedicated to basic and translational cancer research in the context of the tumor microenvironment and closely cooperates with the Goethe University Frankfurt and the Frankfurt University Hospital. It provides access to a broad variety of core facilities and an excellent scientific environment.  

A Post-Doctoral position (TV-H E13) is available immediately in the group of Florian Greten at the Georg-Speyer-Haus – Institute for Tumor Biology and Experimental Therapy in Frankfurt am Main.

Our group focuses on various aspects of the inflammatory tumor microenvironment (TME) of colorectal cancer (Schmitt & Greten, Nat. Rev. Immunol., 2021) striving to develop therapies targeting stromal cells that will improve standard-of-care therapy (Nicolas et al., Cancer Cell, 2022) or enabling immunotherapy of microsatellite stable tumors (Denk et al., Immunity, 2022). We are looking for highly motivated candidates with an excellent track record and a strong interest in pursuing an academic career in translational oncology. The project aims to identify cellular and molecular mechanisms in the TME suppressing T cell immunity during therapy and to develop concepts that will improve immunotherapies employing state-of-the art preclinical models. Candidates for these positions should have a strong background in tumor biology and immunology and should ideally have experience with mouse models.

Read more about research area of Prof. Dr. Greten on our website.

Requirement

  • You have completed a PhD or equivalent doctoral degree in life sciences.
  • You provide two academic references.
  • The quality of your research is proven by publications in excellent peer-reviewed publications, funding track record and high-profile international collaborations.
  • International research experience is considered as an important advantage.
  • You possess organizational skills and have a cooperative attitude and leadership skills.
  • Your spoken and written English is excellent. German skills are a plus.

Offer

  • We offer an interesting and highly autonomous field of responsibilities.
  • You will work closely with our team of researchers.
  • The position is initially limited for 2 years. An extension is planned.
  • The salary is according to TV-H with all social benefits of the public service.
  • As part of the work-life balance, we offer you a great variety of opportunities, such as flexible working hours and help with balancing your career and family.

Interested?

Please send your application as a single PDF containing a cover letter, a CV and two letters of recommendation by e-mail to:

Bewerbung@georg-speyer-haus.de
Georg-Speyer-Haus
Human Resources
Paul-Ehrlich-Str 42-44
60596 Frankfurt am Main

Our international working environment promotes equal opportunities for men and women, regardless of their nationality, age, race, religion and beliefs, disability and sexual orientation, under criteria of scientific excellence.


Junior Group Leader Tumor Immunology (m/f/d)

The Institute for Tumor Biology and Experimental Therapy, Georg-Speyer-Haus in Frankfurt am Main is an academic non-profit research institute supported by the Federal Ministry of Health and the Ministry for Sciences and Arts of the State of Hessen. The institute is dedicated to basic and translational cancer research in the context of the tumor microenvironment and closely cooperates with the Goethe University Frankfurt and the University Hospital Frankfurt. It provides access to a broad variety of core facilities, an excellent scientific environment and is a partner site in the German Cancer Consortium (DKTK).

At the LOEWE Center Frankfurt Cancer Institute (FCI) interdisciplinary teams collaborate to elucidate molecular mechanisms of tumor pathogenesis and therapy response to develop innovative targeted therapies.

Currently, we are recruiting a FCI-funded Junior Group Leader Tumor Immunology. We are looking for a scientist with proven experience and outstanding research performance in the field of tumor immunology ideally with focus on T-cell immunology. The applicant is expected to have performed excellent research in the area of tumor immunology, e.g. on molecular and cellular mechanisms on response and relapse in malignant disease or experience in the development of innovative immune therapeutic concepts.

Prerequisite for the application is a university degree and doctoral degree. The applicant is expected to have an excellent scientific record with international publication performance, a high degree of scientific commitment and to acquire competitive national and international third-party research funding. In addition, the applicant is expected to participate in the interdisciplinary structure of the FCI and to add a high level of cooperation with all working groups of the FCI, especially in the interdisciplinary clinical translation programs.

Your profile

  • Doctoral degree in life sciences or biotechnology or MD/Ph.D.
  • Previous expertise in cancer immunology research
  • Publication record that is internationally competitive for the stage of the career
  • High level of motivation, communication and learning skills
  • Ability to work in a translational team

We offer

  • An excellent basic and translational research environment
  • A strong interdisciplinary team
  • Development of a scientific profile
  • Integration into structures at the FCI and the local DKTK structures
  • Participation in further training and qualification programs
  • Access to GSH Core Facilities
  • Salary according to TV-H including social benefits
  • Flexible working hours as part of the good work-and-family life balance

Contract period
The position is initially limited to 5 years.

Applications should be submitted until May 31st, 2023, electronically to bewerbung@georg-speyer-haus.de with CV, list of publications, contact information of 2 supporting referees and a 3-4 page research synopsis that both summarizes current / past research accomplishments and outlines the candidate´s research program for the next 5 years.

For further information please contact Prof. Dr. Florian Greten.

Our international working environment promotes equal opportunities for all staff regardless of gender, age, cultural background, nationality, or impairments under criteria of scientific excellence. Applications from women are explicitly welcome. Disabled individuals will be preferred in case of equal qualification.

For Information about the Georg-Speyer-Haus please visit our website. For more information about the FCI please visit our FCI website.