The Transgenic Core Facility (TCF) provides a centralized resource for the generation of mouse models to understand human diseases and assist in developing novel therapies. We provide full support from transgenic design to the generation of the mouse models, depending on the need of the researchers. We make use of the full toolbox of CRISPR/Cas9 applications to generate complex genome engineered mice. Furthermore, the TCF provides standard services such as rederivation, sperm testing and conservation of mouse lines. For a detailed description of the method portfolio, soon you can click here (under construction).
TCF is a central service unit for all working groups of the GSH as well as external research groups.