Tijna Alekseeva completed her Master's thesis in Biomedical Research at the University of Glasgow (UK) and her PhD in Tissue Engineering and Regenerative Medicine at University College London (UK). After her PhD, Tijna was a postdoctoral fellow in the laboratories of Prof. James Kirkpatrick (University Medical Center Mainz) and Prof. Fergal O`Brien at the Royal College of Surgeons in Dublin (Ireland). Tijna has been working as a laboratory manager in AG Sevenich since 2017 and is co-responsible for a variety of experimental projects.
Anna Salamero Boix
Anna Salamero Boix completed her Bachelor's and Master's degree in Biomedical Sciences at the University of Lleida and the Autonomous University in Madrid (Spain). During her bachelor's and master's thesis in Dr. Squatrito's laboratory at the CNIO in Madrid (Spain), Anna worked on the identification of resistance to temozolomide in glioblastoma multiforme. She has been a PhD student in the Sevenich group since October 2016. In the context of her PhD thesis, Anna is working on anti-inflammatory signaling pathways in brain metastases.
Michael Schulz studied Biology at the University of Bayreuth and completed his Master's thesis in Molecular Ecology in the group of Prof. Begemann. Michael investigated the role of the retinoic acid (RA) signaling pathway in melanophore development in zebrafish (Danio rerio). By modulating the pathway, he was able to show that RA exerts a regulatory influence on the number of melanophores in embryonic development. His work focuses on molecular and cellular changes in the tumor microenvironment during the course of brain metastasis and following the application of standard therapy with the goal of identifying molecular modulators of inflammatory processes in brain metastases.
Julian Anthes received his Bachelor degree in Biology from the Philipps-University of Marburg. During his Bachelor thesis in the group of Prof. Dr. Jude Przyborski, he worked on the protein translocation in with Plasmodium falciparum infected red blood cells. Julian joined the AG Sevenich as a Master student in 2019 within the molecular medicine studies at the Goethe-University of Frankfurt am Main. In his thesis he analyzed effects of macrophage depletion on radio-immunotherapy in breast-to-brain metastasis. In his PhD project his main research focuses on the effect of immune-checkpoint inhibitors to improve the standard-of-care treatment to develop adjuvant therapies for brain metastases.
Dominic Menger studied Applied Biology for Medicine and Pharmacy at the Fresenius University of Applied Sciences in Idstein. In his bachelor thesis he investigated inflammation-induced changes in megakaryocytes and platelets in the group of Prof. Dr. Klaus Scholich at the Institute of Clinical Pharmacology at the University Hospital of the Goethe University in Frankfurt am Main. Then he studied the master's degree in molecular medicine at the Frankfurt Goethe University. In the master's thesis in the working group of Dr. Lisa Sevenich he examined the role of colony stimulating factor 2 (CSF2) on macrophages and microglia in a breast-to-brain metastasis model. Starting his doctoral thesis in the group of Dr. Lisa Sevenich in May 2021, Dominic will focus on the role and formation of lymphatic vessels in the recruitment of T cells in brain metastases.
Aylin Möckl studied molecular biology at the Johannes Gutenberg University in Mainz. During her bachelor thesis in the group of Prof. Dr. Ari Waisman, she investigated the role of the Nf-κB signaling pathway in multiple sclerosis. She completed her master's degree in molecular medicine at the Goethe University in Frankfurt am Main. During her master thesis in the group of Dr. Lisa Sevenich, Aylin investigated the role of specific genes in the development of brain metastases for the generation of a spontaneous breast-to-brain metastasis model. In April 2020 she started her PhD in the group of Dr. Lisa Sevenich and investigates the effects of CSF1 and CSF2 on brain metastasis.
Abdallah El Sheikha
Abdallah El Sheikha studied medicine at the JLU Giessen. Since 2021 he started his MD thesis in the lab of Dr. Lisa Sevenich. His thesis is focussed on the effects of different radio- and immunotherapies on the immunologic microenvironment of brain metastasis. His project is supported by a grant from the Mildred-Scheel-Nachwuchszentrum (MSNZ).