Forschen für das Leben
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de

Dr. Phillip Grote

gsh-pgrote-2021

Head of TCF

Tel: +4969-63395-620
E-Mail: Ph.Grote@georg-speyer-haus.de

i-GONAD

Ohtsuka M, Sato M.
i-GONAD: A method for generating genome-edited animals without ex vivo handling of embryos.
Dev Groth Differ Wiley, Jun 2019, Vol 61 (I5), 306-315.
Onlinelibrary Wiley or view PDF

Gurumurthy CB, Sato M, Nakamura A, Inui M, Kawano N, Islam MA, Ogiwara S, Takabayashi S, Matsuyama M, Nakagawa S, Miura H, Ohtsuka M.
Creation of CRISPR-based germline-genome-engineered mice without ex vivo handling of zygotes by i-GONAD.
Nature Protocols, Jul 2019, Vol 14, 2452–2482.
nprot by Springer US

 

Tetraploid/Diploid Aggregation

George SHL, Gertsenstein M, Vintersten K, Korets-Smith E, Murphy J, Stevens ME, Haigh JJ, Nagy A.
Developmental and adult phenotyping directly from mutant embryonic stem cells.
Proc Natl Acad Sci USA, March 2007, 104 (11), 4455-4460.
PNAS or view PDF

 

Auxin Induced Degradation of Proteins

Yesbolatova A, Saito Y, Kitamoto N, Makino-Itou H, Ajima R, Nakano R, Nakaoka H, Fukui K, Gamo K, Tominari Y, Takeuchi H, Saga Y, Hayashi K ichiro, Kanemaki MT.
he auxin-inducible degron 2 technology provides sharp degradation control in yeast, mammalian cells, and mice.
Nature Communications, Nov 2020 (11: 5701).
Nat Comm or view PDF