Dr. Arnaud Descot
Dr. Arnaud Descot studied chemistry at the Ecole Nationale Supérieure de Chimie in Montpellier (France) and structural and cellular biology at the University of Montpellier (France). After graduating, Arnaud moved to the Max Planck Institute of Biochemistry in Martinsried in the group of Guido Posern within the department of Axel Ullrich. During his PhD, Arnaud contributed to the characterisation of the newly discovered Rho-Actin signal transduction pathway. In 2012 he joined, as a postdoctoral fellow, the group of Thordur Oskarsson at the DKFZ/HI-STEM in Heidelberg to work on matricellular proteins essential for the establishment of metastatic niches. By end of 2017, he joined the Medyouf group to study the molecular changes affecting the bone marrow microenvironment as well as explore cellular and molecular mechanisms involved in tumour immune escape.
Ivan war Forscher am GSH. Wir wünschen für seine berufliche und private Zukunft bestes Gelingen und bedanken uns für den spannenden Austausch in unserem Forschungsinstitut.
Cristobal Fernandez Santiago
Cristóbal studierte Biochemie an der Universität Córdoba (Spanien), wo er in der Abteilung für physikalische Chemie wertvolle Forschungserfahrung sammelte, indem er im Rahmen seiner Bachelorarbeit computergestützte Instrumente zur Entwicklung von Medikamenten zur Behandlung der akuten myeloischen Leukämie (AML) einsetzte. Anschließend absolvierte er seinen Master in Biotherapeutika am University College Dublin (Irland), wo er sich auf das therapeutische Potenzial monoklonaler Antikörper konzentrierte. Im Oktober 2021 trat er der Gruppe von Dr. Medyouf als Doktorand im Rahmen eines von der EU finanzierten innovativen Ausbildungsnetzwerks INTERCEPT MDS bei. Seine Forschung wird sich auf die weitere Entwicklung und Nutzung modularer und äußerst vielseitiger organotypischer 3D-Umgebungen des menschlichen Knochenmarks (3D HOMEs) konzentrieren, um die Biologie menschlicher myelodysplastischer Syndrome zu untersuchen und Mittel zur Krankheitsbekämpfung zu erforschen.
Anna-Lena received her bachelor‘s degree in Biosciences from Heidelberg University and her master’s degree in Biology with specialization in Immunology from Freiburg University. During her master thesis, she studied the influence of environmental factors on the pathology of systemic lupus erythematosus. In November 2020, she joined the Medyouf group as a PhD student to study the role of bone marrow structural cells in hematologic malignancies.
Alexander received his bachelor’s degree in biology from the Hamburg University with specialization in genetics and immunology. He then went on to study molecular medicine at the Goethe University Frankfurt am Main and gained research experience in the group of Lisa Westerberg at the Karolinska Institute in Stockholm (Sweden) where he worked on immunodeficiencies linked to the Wiskott-Aldrich Syndrome protein. During his master thesis he joined Lisa Sevenich’s group and investigated the therapeutic targeting of tumor-associated macrophages and microglia in the tumor microenvironment of brain metastasis. In 2018, he joined the Medyouf group as a PhD student to study the role of extra-cellular matrix proteins in human bone metastasis.
Irene holds a master in Integrated Quality Management for Environmental and Occupational Risk Prevention, as well as a master and a PhD in Molecular and Cellular Immunology from the University of Granada (Spain), where she characterized the dendritic cells isolated from spontaneously aborted embryos. In 2008, Irene moved to Berlin and worked as a research assistant at the department of internal medicine of the Berlin Charité. She joined Dr. Medyouf’s group in February 2015 and is currently responsible for lab management and the development of improved culture conditions for primary cells obtained from patient biopsies.
Ioanna received her bachelor’s degree in Biotechnology from the University of Applied Sciences in Darmstadt and was trained in the group of Prof. Dr. Claudia Fournier at the GSI Helmholtz Centre for Heavy Ion Research in Darmstadt. She then pursued her master’s degree in Technical Biology at the Technical University of Darmstadt. In 2019 she joined Dr. Medyouf’s group for her master thesis. Her main research focuses on the biology of NK cells in tumor contexts.
Maresa received her training as a biological technical assistant in Überlingen/Bodensee. She joined the Georg-Speyer-Haus in 1999. In 2016 she switched to the Medyouf-Group to assist lab members in project related experiments and mouse colonies management.