Research Groups at the Georg-Speyer Haus
The Georg-Speyer-Haus engages in cutting-edge international research in the field of tumor microenvironment (TME). Supported by modern state-of-the-art technical platforms, 10 groups led by international scientists are currently working on various aspects of the TME in colorectal cancer, breast cancer, pancreatic cancer, brain tumors and leukemia.
Research Area 1
Tumour Microenvironment – Pathogenesis and Target Structures
Prof. Dr. Melek Canan Arkan
Diet, Energy Metabolism, and Cancer
Prof. Dr. Henner Farin
Experimental models of the colon cancer microenvironment
![[Translate to English:]](/fileadmin/_processed_/5/2/csm_Farin-Henner-3045_2ebe938116.jpg "[Translate to English:]")
Prof. Dr. Florian Greten
Therapeutic interventions in the tumor microenvironment
Dr. Marco Seehawer
Histone modifier in tumor onset, progression, and therapy
Dr. Michael Tyler
Mapping cancer progression with data integration approaches
![[Translate to English:]](/fileadmin/_processed_/b/6/csm_Tyler-Michael-2873-square_008952135f.jpg "[Translate to English:]")
Research Area 2
Experimental Therapy
Dr. Phillip Grote
The role of long, non-protein coding RNAs (lncRNAs) in gene and genome regulation
![[Translate to English:]](/fileadmin/_processed_/a/c/csm_Grote-Phillip-1_f6d8eae90c.jpg "[Translate to English:]")
Prof. Dr. Sina Oppermann
Functional Precision Oncology
Dr. Zuzana Tatarova
DKTK Research Group for Therapy Resistance
Dr. Mélanie Tichet
Immunoregulatory mechanisms in the tumor microenvironment and resistance to therapy
![[Translate to English:]](/fileadmin/_processed_/4/3/csm_Tichet-Melanie-2669_560d1a47c2.jpg "[Translate to English:]")