Spatial Biology Core Facility
Focus
The Spatial Biology Core Facility (SCF) provides cutting-edge technologies for high-resolution spatial gene and protein profiling in tumor tissues and the tumor microenvironment.
Our platforms for spatial transcriptomics include Xenium and Visium HD (10x Genomics) as well as GeoMx (Bruker Spatial Biology), while spatial proteome profiling is performed using COMET, LabSat (Bio-Techne Spatial), PhenoImager (Quanterix), followed by HALO-based image analysis (Indica Labs).
The facility is led by PD Dr. Yvonne Reiss, who oversees platform implementation and operational workflows. Spatial transcriptomics services are coordinated by staff scientist Dr. Jonathan Schupp and Dr. Jennifer Lun. Spatial proteome profiling, including custom high-plex immunofluorescence panel design, is directed by Dr. Reiss with support of Lejla Kovacevic Colpa (doctoral researcher). Prof. Karl H. Plate serves as an expert pathology advisor to the facility.
In addition to providing core services, the SCF team conducts extramurally funded independent research focused on the immuno-oncology of malignant brain tumors.
Request + Contact
While our primary focus is supporting internal Georg-Speyer-Haus research groups, external investigators are welcome to contact us for information and project requests at SCF[at]georg-speyer-haus.de.




