Research
Georg-Speyer-Haus. Foto: Andreas Reeg, andreasreeg.com
Georg-Speyer-Haus. Foto: Andreas Reeg, andreasreeg.com

Press releases

 

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Extention DFG research group for colorectal cancer

Cell Plasticity in Colorectal Carcinogenesis research group under leadership of Prof. Dr. Greten receives extension for additional 3 years   Colorectal cancer is the second leading cause of death among cancers. Although there have been advancements in diagnosis, therapy in patients with metastases has only been successful in a few patients over the past 60… [mehr]

Fighting Colorectal Cancer with Killer Cells

Scientists have shown for the 1st time in mini-tumors from the lab that genetically modified defense cells can successfully destroy colon cancer cells. Dabei setzen die Wissenschaftler am GSH auf einen die neue Krebsimmuntherapie mit genmodifizierten natürlichen Killerzellen. Mit den patientenspezifischen Tumorkulturen können Wissenschaftler jetzt im Labor prüfen, wie gut diese bei einzelnen Patienten anschlagen.… [mehr]

Colorectal cancer: Local mediator sets colon cells onto wrong track

As one of the most important biomarkers in colorectal cancer, Wnt has been identified as a potentially target for new colorectal cancer therapies. The signal molecules of the Wnt family are essential messengers for the continuous renewal of our highly stressed intestinal mucosa. However, too much Wnt is a frequent trigger for colorectal cancer. Wnt… [mehr]

Previous director receives Zukunftspreis 2018

22nd German Future Award goes to the project Protection in the Absence of an Immune System - the Life-Saving Innovation against Dangerous Viruses | Prof. Dr. Helga Rübsamen-Schaeff, the director of Georg-Speyer-Haus from 1987-1993, together with Dr. Holger Zimmermann, received the German Zukunftspreis 2018 for their contribution to the company AiCuris AG, Wuppertal, founded by… [mehr]

EMBO Young Investigator Award for Hind Medyouf

Dr. Hind Medyouf awarded with EMBO YIP. Dr. Hind Medyouf, Group Leader at the Institute for Tumor Biology and Experimental Therapy and the Frankfurt Cancer Institute, has been awarded the prestigious European Molecular Biology Organization (EMBO) Young Investigator Programme (YIP) for the year 2018. She joins an active network of more than 100 current and… [mehr]

Research grant for Ewelina Czlonka

Ewelina Czlonka receives the José Carreras Leukemia Foundation research grant for her doctoral thesis | The José Carreras Leukemia Foundation is once again funding young scientists who are developing innovative and promising research to treat leukemia and related blood disorders. One of the research grants is awarded to our young scientist Ewelina Czlonka with the… [mehr]

Dynamic formation of microvillus inclusions

Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids Using intestinal organoids from Munc18-2-/- mice we show that the phenotypic manifestation of microvillus inclusion disease is critically linked to the enterocyte differentiation state. Live-cell imaging showed that microvillus inclusions gradually form either intracellularly or by plasma membrane internalization. Microvillus inclusion disease (MVID)… [mehr]

HOW CANCER CELLS HIBERNATE

Joint priority program investigates the development of bone metastases Over the next six years, scientists from all over Germany will work closely together to detect bone metastases at an early stage after a previous breast or prostate cancer and to prevent their development. A total of 7.8 million euros will be available over the next… [mehr]

Neuer Mechanismus der T Zellaktivierung während der frühen Kolonkarzinogenese entschlüsselt

Neuer Mechanismus der T Zellaktivierung während der frühen Kolonkarzinogenese entschlüsselt Krebserkrankungen entstehen aus unkontrolliertem Wachstum mutierter Körperzellen, die im Laufe der Erkrankung in gesundes Gewebe eindringen und diese schädigen. Ein wichtiger Grund für die Expansion früher maligner Läsionen ist die Möglichkeit der Tumorzellen einer Erkennung durch das Immunsystem, wie z.B. T Zellen zu entgehen. Interessanterweise… [mehr]

Wissenschaftsrat gibt Bauförderempfehlung für FCI

Wissenschaftsrat gibt Förderempfehlung für den Bau des Frankfurt Cancer Institutes am Campus Niederrad | Frankfurter Forscher:innen wollen neue Wege in der translationalen Krebsforschung gehen und haben hierfür den Bau eines hochmodernen Institutes am Campus Niederrad beantragt. Nun hat der Wissenschaftsrat die Förderung dieses Neubaus empfohlen. Gemeinsam werden das Land Hessen und der Bund sowie die… [mehr]

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