Georg-Speyer-Haus. Foto: Andreas Reeg, Research for Life
Georg-Speyer-Haus. Foto: Andreas Reeg,
Georg-Speyer-Haus. Foto: Andreas Reeg,
Georg-Speyer-Haus. Foto: Andreas Reeg,

Solidarity with scientists from Ukraine

GSH supports initiative #ScienceForUkraine for scientists from Ukraine by offering positions for scientists (undergrad, masters, PhDs, postdoctoral fellows, and associates). Read more ->

New insights in rectal carcinoma therapy

Research team from GSH, KGU & FCI discovered new resistance mechanism in rectal cancer therapy in which inflammatory connective tissue cells decrease response to radiochemotherapy. Read more ->

Diversity at the research institute

Georg-Speyer-Haus is part of Germany’s largest diversity network and is expressly committed to diversity in the work environment. With the Diversity Charter, GSH implements a variety of concepts and measures along all diversity dimensions as part of sustainable diversity management. Read more ->

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Beug Foundation Research Award for Dr. Sevenich on metastasis research

This year's 2019 Beug Foundation Metastasis Research Award goes to Dr. Lisa Sevenich for her efforts in studying T-cell responses in brain metastases. "I am very honored by this award. The grant from the Beug Foundation will allow us to study new types of aspects of the complex interactions between tumor cells and immune cells… [mehr]

Prof. Dr. Krause receives project funding from EKFS

Else Kroener-Fresenius-Foundation funds research project of Prof. Dr. Daniela Krause The main focus of the research group headed by Prof. Dr. Daniela Krause is the extracellular matrix in the bone marrow to improve normal and inhibit malignant blood formation. The funding by the EKF Foundation enables the lab unit of Prof. Dr. Krause to investigate… [mehr]

Extention DFG research group for colorectal cancer

Cell Plasticity in Colorectal Carcinogenesis research group under leadership of Prof. Dr. Greten receives extension for additional 3 years   Colorectal cancer is the second leading cause of death among cancers. Although there have been advancements in diagnosis, therapy in patients with metastases has only been successful in a few patients over the past 60… [mehr]

Fighting Colorectal Cancer with Killer Cells

Scientists have shown for the 1st time in mini-tumors from the lab that genetically modified defense cells can successfully destroy colon cancer cells. Dabei setzen die Wissenschaftler am GSH auf einen die neue Krebsimmuntherapie mit genmodifizierten natürlichen Killerzellen. Mit den patientenspezifischen Tumorkulturen können Wissenschaftler jetzt im Labor prüfen, wie gut diese bei einzelnen Patienten anschlagen.… [mehr]

Colorectal cancer: Local mediator sets colon cells onto wrong track

As one of the most important biomarkers in colorectal cancer, Wnt has been identified as a potentially target for new colorectal cancer therapies. The signal molecules of the Wnt family are essential messengers for the continuous renewal of our highly stressed intestinal mucosa. However, too much Wnt is a frequent trigger for colorectal cancer. Wnt… [mehr]

Previous director receives Zukunftspreis 2018

22nd German Future Award goes to the project Protection in the Absence of an Immune System - the Life-Saving Innovation against Dangerous Viruses | Prof. Dr. Helga Rübsamen-Schaeff, the director of Georg-Speyer-Haus from 1987-1993, together with Dr. Holger Zimmermann, received the German Zukunftspreis 2018 for their contribution to the company AiCuris AG, Wuppertal, founded by… [mehr]

EMBO Young Investigator Award for Hind Medyouf

Dr. Hind Medyouf awarded with EMBO YIP. Dr. Hind Medyouf, Group Leader at the Institute for Tumor Biology and Experimental Therapy and the Frankfurt Cancer Institute, has been awarded the prestigious European Molecular Biology Organization (EMBO) Young Investigator Programme (YIP) for the year 2018. She joins an active network of more than 100 current and… [mehr]

Research grant for Ewelina Czlonka

Ewelina Czlonka receives the José Carreras Leukemia Foundation research grant for her doctoral thesis | The José Carreras Leukemia Foundation is once again funding young scientists who are developing innovative and promising research to treat leukemia and related blood disorders. One of the research grants is awarded to our young scientist Ewelina Czlonka with the… [mehr]

Dynamic formation of microvillus inclusions

Dynamic Formation of Microvillus Inclusions During Enterocyte Differentiation in Munc18-2–Deficient Intestinal Organoids Using intestinal organoids from Munc18-2-/- mice we show that the phenotypic manifestation of microvillus inclusion disease is critically linked to the enterocyte differentiation state. Live-cell imaging showed that microvillus inclusions gradually form either intracellularly or by plasma membrane internalization. Microvillus inclusion disease (MVID)… [mehr]


Joint priority program investigates the development of bone metastases Over the next six years, scientists from all over Germany will work closely together to detect bone metastases at an early stage after a previous breast or prostate cancer and to prevent their development. A total of 7.8 million euros will be available over the next… [mehr]

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