Research
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de
Georg-Speyer-Haus. Foto: Andreas Reeg, Tel: +40-171-5449247, andreas.reeg@t-online.de, www.andreasreeg.de

Dr. Madina Karimova

GSH Dr. Madina Karimova

T: +4969-63395-620
F: +4969-63395-297
Email: Karimova@gsh.uni-frankfurt.de

Peer-reviewed primary publications

Madina Karimova*, Victoria Splith*, Janet Karpinski, M. Teresa Pisabarro & Frank Buchholz.
Discovery of Nigri/nox and Panto/pox site-specific recombinase systems facilitates advanced genome engineering.
Nature Scientific Reports, 2016
PubMed

Madina Karimova*, Niklas Beschorner*, Werner Dammermann, Jan Chemnitz, Daniela Indenbirken, Jan-Hendrik Bockmann, Adam Grundhoff, Stefan Lüth, Frank Buchholz, Julian Schulze zur Wiesch & Joachim Hauber.
CRISPR/Cas9 nickase-mediated disruption of hepatitis B virus open reading frame S and X.
Nature Scientific Reports, 2015
PubMed

Loregger A, Cook EC, Nelson JK, Moeton M, Sharpe LJ, Engberg S, Karimova M, Lambert G, Brown AJ, Zelcer N.
A MARCH6 and IDOL E3 Ubiquitin Ligase Circuit Uncouples Cholesterol Synthesis from Lipoprotein Uptake in Hepatocytes.
Mol Cell Biol, 2015
PubMed

Madina Karimova, Josephine Abi-Ghanem, Vineeth Surendranath, M. Teresa Pisabarro, Frank Buchholz.
Vika/vox, a novel efficient and specific Cre/loxP-like site-specific recombination system.
Nucleic Acids Research, 2012
PubMed

Josephine Abi-Ghanem, Janet Chusainow, Madina Karimova, Christopher Spiegel, Joachim Hauber, Frank Buchholz, M. Teresa Pisabarro.
Engineering of a target site-specific recombinase by a combined evolution- and structure-guided approach.
Nucleic Acids Research, 2012
PubMed

Patents
Patent application: no. 14176629.5 Karimova M., Joachim Hauber, Frank Buchholz. “Method for Hepatitis B virus inactivation” (2014) (CRISPR/Cas9)

Patent Application: no. 12 177 608.2 Karimova M. and Buchholz F. „Protein with recombinase activity for site-specific DNA-recombination“ (2012) (Vika/vox)

Other publications
Karimova M.R., Sharipova M.R. / Constructing Glutamylendopeptidase Gene Bacillus intermedius with Modified Regulation Area // Proceedings of the VII Science Conference for Young Scientists, Postgraduate and Undergraduate Students of SEC KSU “Materials and Technologies of XXI century”. – Kazan, 2007. – p.7.

Karimova M.R., Mikhalova E.O., Sharipova M.R./ Subtilisin-like Proteinases Bacillus intermedius Secreted by Recombinant Strain Bacillus subtilis AJ 73: Physical-Chemical Properties // Proceedings of the XV International Conference for Undergraduate and Graduate Students and Young Scientists “LOMONOSOV- 2007”.– Moscow, 2007 – p.27-28.

Mikhalova E.O., Karimova M.R., Rudenskaya G.N., Sharipova M.R./ Subtilisinlike Proteinases Bacillus intermedius Secreted by Recombinant Strain Bacillus subtilis AJ 73// Biology –science of 21st century: Proceedings / 10th International Conference-School in Pushino for Young Scientists. – Pushino, 2006. –p.71.